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Tirzepatide

Metabolic Peptide

Tirzepatide

Dual GIP/GLP-1 receptor agonist studied in glucose regulation models.

$100.00

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Don't forget your reconstitution solution

Bacteriostatic Water 30mL

$14.99

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HPLC-MS + endotoxin

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Plain outer box

Research Use Only

Not for human or veterinary consumption. For laboratory and in-vitro research purposes only.

Description

Tirzepatide is a dual GIP/GLP-1 receptor agonist investigated in research on insulin sensitivity and glycemic response.

Sold as a lyophilized peptide for non-clinical laboratory use.

Reconstitution

Reconstitute with bacteriostatic water in your preferred ratio. Store reconstituted vials refrigerated (2–8 °C) and use within recommended timeframes for your protocol.

Storage

Unreconstituted lyophilized powder stable at room temperature for short periods; refrigerate (2–8 °C) for long-term storage. Avoid repeat freeze/thaw cycles.

Product Specs
Dose
10mg
Purity
≥ 99%
Form
Lyophilized powder
Storage
Refrigerate after reconstitution
Origin
USA — synthesized & shipped domestically
Testing
HPLC-MS, MALDI, endotoxin screen
View Certificate of Analysis

Research Overview

Tirzepatide is a synthetic 39-amino-acid peptide built as a dual agonist of the GIP and GLP-1 receptors. It is one of the most extensively characterized incretin-mimetic research peptides of the last decade, frequently used as a benchmark in comparative metabolic studies.

Its sequence is based on the native GIP backbone with strategic substitutions and a C20 fatty diacid moiety that prolongs circulating half-life in research models. Tirzepatide is supplied as a sterile lyophilized powder for in-vitro and laboratory use.

Mechanism of Action

Tirzepatide simultaneously engages GIP and GLP-1 receptors on pancreatic, adipose, and central nervous system tissues in research models. Co-activation has been studied for its effects on insulin secretion kinetics, glucagon suppression, and downstream signaling cascades.

Research Applications

  • Dual incretin receptor pharmacology
  • Glycemic response and beta-cell signaling studies
  • Adipose and energy-balance research
  • Comparative agonist potency assays

Study Highlights

Balanced dual agonism

Published in-vitro work has characterized tirzepatide's biased signaling profile, with notable activity at GIP receptors relative to native GIP and full agonism at GLP-1 receptors.

Long-acting design

The fatty acid moiety supports albumin binding, producing a research half-life suitable for once-weekly preclinical dosing models.

Reconstitution & Handling

Solubility
Soluble in bacteriostatic water
Reported half-life
≈ 5 days (research models)
Storage
Lyophilized: 2–8°C. Reconstituted: refrigerate, use within 30 days.

Certificate of Analysis

Lot / Batch

QP-2025-7609

Download PDF
Product
Tirzepatide
Manufacture date
2025-10-02
Test date
2025-10-05
Expiration
2028-10-02
Appearance
White to off-white lyophilized powder
Identity
Confirmed — matches reference standard
Purity (HPLC)
99.70%
Water content (KF)
1.30%
Endotoxin (LAL)
< 0.09 EU/mg
Bioburden
< 1 CFU / vial
Analytical methods
RP-HPLC, ESI-MS, MALDI-TOF, LAL endotoxin assay
Released by
QPUSA Quality Assurance Lab
Results above represent independent laboratory testing of the referenced batch. Full PDF includes HPLC chromatogram, mass-spec trace, and analyst signature.

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