Neuropeptide
PE-22-28
Synthetic peptide derived from spadin studied in neurological research.
$70.00
Free shipping on orders over $300 · Same-day dispatch before 2PM EST
Select Option
Volume Discounts
Don't forget your reconstitution solution
Bacteriostatic Water 30mL
$14.99
Purchase Options
Lab Verified
HPLC-MS + endotoxin
Same-Day Ship
Orders by 2PM EST
Damage Coverage
Free replacement
Discreet Packaging
Plain outer box
Research Use Only
Not for human or veterinary consumption. For laboratory and in-vitro research purposes only.
Description
PE-22-28 is a synthetic peptide derived from spadin for research on TREK-1 channel studies.
Reconstitution
Reconstitute with bacteriostatic water in your preferred ratio. Store reconstituted vials refrigerated (2–8 °C) and use within recommended timeframes for your protocol.
Storage
Unreconstituted lyophilized powder stable at room temperature for short periods; refrigerate (2–8 °C) for long-term storage. Avoid repeat freeze/thaw cycles.
- Dose
- 5mg
- Purity
- ≥ 99%
- Form
- Lyophilized powder
- Storage
- Refrigerate after reconstitution
- Origin
- USA — synthesized & shipped domestically
- Testing
- HPLC-MS, MALDI, endotoxin screen
Research Overview
PE-22-28 is a synthetic 7-amino-acid peptide derived from the spadin sequence. It is studied as a TREK-1 potassium-channel blocker in neurological research models.
Mechanism of Action
Selectively blocks TREK-1 (KCNK2) two-pore-domain potassium channels in research models, with downstream effects on neuronal excitability.
Research Applications
- TREK-1 channel pharmacology
- Neuronal excitability research
- Spadin-pathway studies
Reconstitution & Handling
Certificate of Analysis
Lot / Batch
QP-2025-6285
- Product
- PE-22-28
- Manufacture date
- 2025-06-22
- Test date
- 2025-06-25
- Expiration
- 2028-06-22
- Appearance
- White to off-white lyophilized powder
- Identity
- Confirmed — matches reference standard
- Purity (HPLC)
- 99.90%
- Water content (KF)
- 1.70%
- Endotoxin (LAL)
- < 0.05 EU/mg
- Bioburden
- < 1 CFU / vial
- Analytical methods
- RP-HPLC, ESI-MS, MALDI-TOF, LAL endotoxin assay
- Released by
- QPUSA Quality Assurance Lab
